Sequence-based prediction of physicochemical interactions at protein functional sites using a function-and-interaction-annotated domain profile database.
Min HanYifan SongJiaqiang QianDengming MingPublished in: BMC Bioinform. (2018)
Keyphrases
- protein interaction
- database
- protein structure prediction
- amino acids
- protein families
- protein protein interactions
- predicting protein
- database systems
- tertiary structure
- experimentally determined
- remote homology detection
- protein tertiary structure
- sequence similarity
- interaction patterns
- physicochemical properties
- sequence databases
- multiple sequence alignments
- subcellular localization
- databases
- gene expression
- sequence alignment
- computational methods
- biological data
- biological systems
- relational databases
- prediction accuracy
- protein function
- drug design
- contact map
- domain specific
- protein structure
- protein sequences
- protein fold recognition
- contact maps
- protein secondary structure
- cellular processes
- psi blast
- sequence analysis
- protein interaction data
- protein protein
- computational biology
- user profiles
- protein complexes
- multiple sequence alignment