Selection of representative SNP sets for genome-wide association studies: a metaheuristic approach.
Gürkan ÜstünkarSüreyya Özögür-AkyüzGerhard-Wilhelm WeberChristoph M. FriedrichYesim Aydin SonPublished in: Optim. Lett. (2012)
Keyphrases
- metaheuristic
- genome wide association studies
- genome wide
- tabu search
- scatter search
- ant colony optimization
- simulated annealing
- optimization problems
- combinatorial optimization
- path relinking
- genetic algorithm
- search space
- single nucleotide polymorphisms
- optimal solution
- vehicle routing problem
- iterated local search
- high throughput
- benchmark instances
- complex diseases
- particle swarm optimization
- variable neighborhood search
- linkage disequilibrium
- biological data
- human genome
- traveling salesman problem
- guided local search
- objective function
- search algorithm
- statistical methods
- pairwise
- lower bound