Identifying novel associations in GWAS by hierarchical Bayesian latent variable detection of differentially misclassified phenotypes.
Afrah ShafquatRonald G. CrystalJason G. MezeyPublished in: BMC Bioinform. (2020)
Keyphrases
- hierarchical bayesian
- latent variables
- genome wide association studies
- variational inference
- posterior distribution
- topic models
- probabilistic model
- random variables
- bayesian inference
- gibbs sampling
- probabilistic graphical models
- genome wide
- approximate inference
- gaussian process
- biological data
- prior knowledge
- latent dirichlet allocation
- data points
- hidden variables
- factor graphs
- high throughput
- active learning