Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays.
Fei YeWeiyao ZhangXiaoqing YeJia JinZhengbing LvCheng LuoPublished in: J. Chem. Inf. Model. (2018)
Keyphrases
- virtual screening
- drug discovery
- chemical structures
- binding sites
- similarity searching
- high throughput
- mass spectrometry
- protein structure
- structural properties
- scoring function
- molecular biology
- signaling pathways
- systems biology
- data mining
- protein protein interactions
- biological systems
- biological data
- network structure
- nearest neighbor