Searching for protein variants with desired properties using deep generative models.
Yan LiYinying YaoYu XiaMingjing TangPublished in: BMC Bioinform. (2023)
Keyphrases
- generative model
- probabilistic model
- mixture model
- hierarchical hidden markov models
- discriminative models
- discriminative learning
- representational power
- em algorithm
- prior knowledge
- topic models
- deep belief networks
- expectation maximization
- conditional random fields
- hidden variables
- semi supervised
- object categories
- protein sequences
- discriminatively trained