An Expectation-Maximization Algorithm for Analysis of Evolution of Exon-Intron Structure of Eukaryotic Genes.
Liran CarmelIgor B. RogozinYuri I. WolfEugene V. KooninPublished in: Comparative Genomics (2005)
Keyphrases
- expectation maximization
- preprocessing
- detection algorithm
- learning algorithm
- simulated annealing
- objective function
- em algorithm
- graph structure
- tree structure
- segmentation algorithm
- dynamic programming
- k means
- optimal solution
- comparative analysis
- maximum likelihood
- parameter estimation
- gene expression
- worst case
- data analysis
- particle swarm optimization
- microarray
- np hard
- dna sequences
- computational complexity
- similarity measure