Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins.
Young-Rae ChoAidong ZhangPublished in: BMC Bioinform. (2010)
Keyphrases
- functional modules
- protein protein interactions
- interaction networks
- protein interaction networks
- protein interaction
- predicting protein
- biological networks
- protein function
- protein function prediction
- network analysis
- biological processes
- mass spectrometry
- protein protein interaction networks
- ppi networks
- protein complexes
- complex networks
- gene products
- computational methods
- biomedical literature
- network structure
- high throughput
- gene ontology
- signal transduction pathways
- gene expression
- functional units
- drug design
- gene regulatory networks
- high precision
- complex systems
- information flow
- structural properties
- transcriptional regulatory