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A physicochemical descriptor based method for effective and rapid screening of dual inhibitors against BACE-1 and GSK-3β as targets for Alzheimer's disease.
Akhil Kumar
Gaurava Srivastava
Ashok Sharma
Published in:
Comput. Biol. Chem. (2017)
Keyphrases
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high accuracy
computationally efficient
similarity measure
objective function
significant improvement
cost function
probabilistic model
high precision
preprocessing
pairwise
dynamic programming
clustering method
detection method
neural network
object recognition
segmentation method