Parameter estimation of qualitative biological regulatory networks on high performance computing hardware.
Muhammad Tariq SaeedJamil AhmadJan BaumbachJosch PaulingAamir ShafiRehan Zafar ParachaAsad HayatAmjad AliPublished in: BMC Syst. Biol. (2018)
Keyphrases
- parameter estimation
- regulatory networks
- high performance computing
- massively parallel
- computing systems
- gene expression
- microarray
- gene regulatory networks
- maximum likelihood
- gene expression data
- least squares
- biological data
- parallel computing
- low cost
- model selection
- statistical models
- markov random field
- biological systems
- computing resources
- structure learning
- computational biology
- em algorithm
- systems biology
- microarray data
- computer systems
- grid computing
- computing environments
- expectation maximization
- energy efficiency
- protein protein interactions
- high throughput
- approximate inference
- biological processes
- transcription factors
- machine learning
- image sequences
- databases
- fault tolerance
- image processing
- data warehouse
- data mining