Protein network-based Lasso regression model for the construction of disease-miRNA functional interactions.
Ala QabajaMohammed Al-ShalalfaTarek A. BismarReda AlhajjPublished in: EURASIP J. Bioinform. Syst. Biol. (2013)
Keyphrases
- regression model
- gene function
- gene expression
- post transcriptional
- group lasso
- generalized linear models
- protein interaction
- gene ontology
- saccharomyces cerevisiae
- regulatory networks
- biological knowledge
- model selection
- gene regulation
- protein protein interactions
- interaction networks
- genome wide
- secondary structure
- biomedical literature
- expression profiles
- microarray
- protein function
- differentially expressed genes
- protein protein interaction networks
- computational methods
- gene regulatory networks
- gene expression data
- regression methods
- microarray data
- protein structure
- amino acids
- binding sites
- regression analysis
- biological processes
- transcription factors
- gene sets
- protein interaction networks
- feature selection
- signaling pathways
- protein families
- protein sequences
- amino acid sequences
- systems biology
- biological data
- gaussian process
- explanatory variables
- functional modules
- multivariate regression
- high throughput
- linear regression
- protein complexes
- logistic regression
- variable selection
- biological information
- semantic similarity
- gene expression profiles
- sample size