ICAT: a novel algorithm to robustly identify cell states following perturbations in single-cell transcriptomes.
Dakota Y. HawkinsDaniel T. ZuchJames HuthNahomie Rodriguez-SastreKelley R. McCutcheonAbigail GlickAlexandra T. LionChristopher F. ThomasAbigail E. DescoteauxWilliam Evan JohnsonCynthia A BradhamPublished in: Bioinform. (2023)
Keyphrases
- preprocessing
- dynamic programming
- optimization algorithm
- high accuracy
- significant improvement
- learning algorithm
- detection algorithm
- simulated annealing
- selection algorithm
- theoretical analysis
- experimental evaluation
- improved algorithm
- times faster
- computational complexity
- expectation maximization
- search space
- cost function
- neural network
- computationally efficient
- segmentation algorithm
- search algorithm
- optimal solution
- segmentation method
- classification algorithm
- path planning
- computational cost
- convex hull
- convergence rate
- similarity measure