A novel yeast hybrid modeling framework integrating Boolean and enzyme-constrained networks enables exploration of the interplay between signaling and metabolism.
Linnea ÖsterbergIván DomenzainJulia MünchJens NielsenStefan HohmannMarija CvijovicPublished in: PLoS Comput. Biol. (2021)
Keyphrases
- modeling framework
- metabolic pathways
- biological networks
- biological data
- ppi networks
- systems biology
- network analysis
- protein interaction networks
- topic modeling
- signal transduction
- functional modules
- gene expression data
- protein protein interactions
- biological systems
- high throughput
- complex networks
- data analysis
- natural language
- regulatory networks
- network structure
- topic models
- information extraction
- protein protein interaction networks