Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetase.
Kaspar ValgepeaKaarel AdambergRanno NahkuPetri-Jaan LahtveeLiisa ArikeRaivo ViluPublished in: BMC Syst. Biol. (2010)
Keyphrases
- systems biology
- metabolic pathways
- escherichia coli
- high throughput
- regulatory networks
- biological systems
- biological data
- gene regulation
- cell cycle
- gene regulatory networks
- biological networks
- molecular biology
- computational biology
- biological processes
- life sciences
- signaling pathways
- interaction networks
- genome wide
- protein protein interactions
- microarray
- data sets
- transcription factors
- protein interaction
- complex systems
- natural language processing
- high dimensional
- data analysis
- saccharomyces cerevisiae
- feature selection