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Mixture models reveal multiple positional bias types in RNA-Seq data and lead to accurate transcript concentration estimates.
Andreas Tuerk
Gregor Wiktorin
Serhat Güler
Published in:
PLoS Comput. Biol. (2017)
Keyphrases
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mixture model
data analysis
data collection
data points
data sets
image processing
gaussian mixture model
high dimensional data
data processing
probabilistic model
prior knowledge
maximum likelihood
expectation maximization
model selection
language model
probability density function
density estimation