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oxBS-MLE: an efficient method to estimate 5-methylcytosine and 5-hydroxymethylcytosine in paired bisulfite and oxidative bisulfite treated DNA.
Zongli Xu
Jack A. Taylor
Yuet-Kin Leung
Shuk-Mei Ho
Liang Niu
Published in:
Bioinform. (2016)
Keyphrases
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experimental evaluation
estimation algorithm
detection method
classification method
classification accuracy
input data
high accuracy
machine learning
cost function
least squares
significant improvement
prior knowledge
evolutionary algorithm
synthetic data
pairwise
statistical methods
preprocessing