On the Power to Detect SNP/Phenotype Association in Candidate Quantitative Trait Loci Genomic Regions: A Simulation Study.
Josep M. ComeronMartin KreitmanFrancisco M. de la VegaPublished in: Pacific Symposium on Biocomputing (2003)
Keyphrases
- simulation study
- genome wide
- high throughput
- single nucleotide polymorphisms
- complex diseases
- linkage disequilibrium
- copy number
- human genome
- genome wide association studies
- high throughput sequencing
- association studies
- coding regions
- genomic data
- dna sequences
- transcription factor binding sites
- monte carlo
- detection method
- biological data
- computational approaches
- microarray
- genotype phenotype
- qualitative and quantitative
- detection algorithm
- automatic detection
- variable selection
- transcription factors
- region of interest
- power consumption
- input image
- dna copy number
- search algorithm
- image features
- search space
- complex background
- protein protein interactions
- computational methods
- statistical methods
- data acquisition