An HMM-based algorithm for evaluating rates of receptor-ligand binding kinetics from thermal fluctuation data.
Lining JuYijie Dylan WangYing HungChien-Fu Jeff WuCheng ZhuPublished in: Bioinform. (2013)
Keyphrases
- input data
- preprocessing
- data sets
- database
- search space
- noisy data
- data sources
- clustering method
- synthetic data
- np hard
- matching algorithm
- experimental data
- data analysis
- computational complexity
- optimal solution
- prior information
- information loss
- detection algorithm
- optimization algorithm
- dimensional data
- particle swarm optimization
- dynamic programming
- hidden markov models
- k means
- similarity measure
- learning algorithm
- data mining techniques
- knowledge discovery
- computational cost
- high dimensional data
- decision trees
- data reduction
- synthetic datasets
- neural network