A robust linear regression based algorithm for automated evaluation of peptide identifications from shotgun proteomics by use of reversed-phase liquid chromatography retention time.
Hua XuLanhao YangMichael A. FreitasPublished in: BMC Bioinform. (2008)
Keyphrases
- cost function
- experimental evaluation
- times faster
- dynamic programming
- learning algorithm
- computational complexity
- closed form
- convergence rate
- high accuracy
- clustering method
- optimal solution
- computationally efficient
- recognition algorithm
- linear programming
- improved algorithm
- matching algorithm
- expectation maximization
- boundary conditions
- training phase
- mass spectrometry
- preprocessing phase
- detection algorithm
- optimization algorithm
- segmentation algorithm
- least squares
- probabilistic model
- computational cost
- long term
- search space
- preprocessing
- similarity measure