Apoptosis centric Bayesian network perturbation analysis of signaling pathways in colorectal cancer for synergistic drug targets discovery.
Pranav SrinivasPublished in: BCB (2014)
Keyphrases
- colorectal cancer
- signaling pathways
- bayesian networks
- regulatory networks
- systems biology
- graphical models
- knowledge discovery
- probabilistic inference
- motif discovery
- gene regulatory networks
- pattern discovery
- computational methods
- structure learning
- data mining
- probabilistic model
- transcription factors
- gene ontology
- protein protein interactions
- conditional independence
- structural properties
- high throughput
- gene expression
- statistical analysis