Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian models.
Dietrich TrümbachCornelia GrafBenno PützClaudia KühneMarcus PanhuysenPeter WeberFlorian HolsboerWolfgang WurstGerhard WelzlJan M. DeussingPublished in: BMC Syst. Biol. (2010)
Keyphrases
- gene expression data
- gaussian model
- gene regulatory networks
- gene expression
- microarray
- gene networks
- microarray data
- regulatory networks
- gene expression analysis
- feature selection
- signaling pathways
- high dimensionality
- neural network
- data sets
- high dimensional data
- biological networks
- high dimensional
- analysis of gene expression data
- conditional independence
- high throughput
- gene selection
- systems biology
- dna microarray
- sequential monte carlo methods
- biological processes
- gene ontology
- image intensity
- network model
- input data
- low dimensional
- support vector machine