Discovery of Multitarget-Directed Ligands against Alzheimer's Disease through Systematic Prediction of Chemical-Protein Interactions.
Jiansong FangYongjie LiRui LiuXiaocong PangChao LiRanyao YangYangyang HeWenwen LianAi-lin LiuGuan-hua DuPublished in: J. Chem. Inf. Model. (2015)
Keyphrases
- protein interaction
- protein protein interactions
- protein complexes
- molecular level
- drug design
- gene expression
- computational methods
- protein protein interaction networks
- protein function
- protein interaction networks
- biological data
- functional modules
- virtual screening
- gene ontology
- biological processes
- biomedical literature
- microarray
- knowledge discovery
- systems biology
- binding sites
- computational approaches
- biological systems
- drug discovery
- data sets
- information extraction
- data mining
- protein interaction data
- databases