Identification of regulatory structure and kinetic parameters of biochemical networks via mixed-integer dynamic optimization.
Gonzalo Guillén-GosálbezAntoni MiróRui AlvesAlbert SorribasLaureano JiménezPublished in: BMC Syst. Biol. (2013)
Keyphrases
- biochemical networks
- mixed integer
- dynamic optimization
- systems biology
- cell cycle
- linear program
- continuous variables
- feasible solution
- nature inspired
- machine learning
- optimal solution
- maximum likelihood
- network structure
- convex hull
- data sets
- linear programming
- dynamic programming
- evolutionary algorithm
- high dimensional
- neural network