A variational approach to parameter estimation in ordinary differential equations.
Daniel KaschekJens TimmerPublished in: BMC Syst. Biol. (2012)
Keyphrases
- parameter estimation
- ordinary differential equations
- differential equations
- dynamic systems
- maximum likelihood
- least squares
- mathematical models
- partial differential equations
- markov random field
- model selection
- numerical solution
- statistical models
- em algorithm
- gene regulatory networks
- energy functional
- approximate inference
- structure learning
- parameter estimation algorithm
- biological systems
- expectation maximization
- maximum likelihood estimation
- machine learning
- image denoising
- higher order
- similarity measure