A segmental maximum a posteriori approach to genome-wide copy number profiling.
Robin AnderssonCarl E. G. BruderArkadiusz PiotrowskiUwe MenzelHelena NordJohanna SandgrenTorgeir R. HvidstenTeresita Diaz de StåhlJan P. DumanskiHenryk Jan KomorowskiPublished in: Bioinform. (2008)
Keyphrases
- maximum a posteriori
- genome wide
- dna copy number
- copy number
- single nucleotide polymorphisms
- high throughput
- markov random field
- map estimation
- image reconstruction
- maximum likelihood
- human genome
- em algorithm
- energy function
- expectation maximization
- noise level
- transcription factors
- parameter estimation
- protein protein interactions
- microarray
- machine learning
- graph cuts
- multiscale
- computer vision