Automatic selection of reference taxa for protein-protein interaction prediction with phylogenetic profiling.
Martin SimonsenStefan MaetschkeMark A. RaganPublished in: Bioinform. (2012)
Keyphrases
- automatic selection
- protein protein interactions
- phylogenetic trees
- multiple sequence alignments
- protein interaction
- predicting protein
- wet lab
- drug design
- protein function prediction
- computational methods
- functional modules
- protein complexes
- gene ontology
- predicting protein protein interactions
- protein function
- computational biology
- biological processes
- high throughput
- network topology
- biological data
- genomic data
- experimentally determined
- ppi networks
- biomedical literature
- systems biology
- protein interaction networks
- secondary structure
- computational approaches
- machine learning
- high speed