An in silico approach combined with in vivo experiments enables the identification of a new protein whose overexpression can compensate for specific respiratory defects in Saccharomyces cerevisiae.
Annie GlatignyLise MathieuChristopher J. HerbertGeneviève DujardinBrigitte MeunierMarie-Hélène Mucchielli-GiorgiPublished in: BMC Syst. Biol. (2011)
Keyphrases
- data analysis
- biological data
- saccharomyces cerevisiae
- drosophila melanogaster
- protein protein interactions
- gene regulatory networks
- homo sapiens
- regulatory networks
- molecular biology
- machine learning
- knowledge discovery
- systems biology
- genomic data
- protein function
- protein interaction networks
- microarray data
- protein protein interaction networks
- protein interaction
- biological processes
- gene expression
- functional modules
- statistical methods
- mass spectrometry
- gene expression data
- protein complexes
- computational methods