Disentangling Direct from Indirect Co-Evolution of Residues in Protein Alignments.
Lukas BurgerErik van NimwegenPublished in: PLoS Comput. Biol. (2010)
Keyphrases
- protein sequences
- amino acids
- protein structure
- multiple sequence alignments
- sequence alignment
- multiple sequence alignment
- multiple alignment
- amino acid sequences
- contact map
- protein function
- protein folding
- protein structure prediction
- amino acid composition
- molecular dynamics simulations
- pairwise
- protein protein
- secondary structure
- computational biology
- protein structure alignment
- physicochemical properties
- protein chains
- protein protein interactions
- computational methods
- binding sites
- molecular biology
- protein structural
- tertiary structure
- biological sequences
- dead end
- drug design
- protein tertiary structure
- fold cross validation
- computational approaches