Inferring global levels of alternative splicing isoforms using a generative model of microarray data.
Ofer ShaiQuaid MorrisBenjamin J. BlencoweBrendan J. FreyPublished in: Bioinform. (2006)
Keyphrases
- generative model
- rna seq
- microarray data
- gene expression
- microarray
- high throughput
- biological data
- gene expression data
- alternative splicing
- gene selection
- probabilistic model
- feature selection
- em algorithm
- expectation maximization
- semi supervised
- genome wide
- systems biology
- high dimensional
- gene expression profiles
- binding sites
- protein protein interactions
- prior knowledge
- sequence data
- biological networks
- microarray datasets
- high dimensionality
- genomic data
- gene sets
- text mining
- data sets
- transcription factors
- data analysis