The challenge of annotating protein sequences: The tale of eight domains of unknown function in Pfam.
Nalin C. W. GoonesekereKrysten ShipelyKevin O'ConnorPublished in: Comput. Biol. Chem. (2010)
Keyphrases
- protein sequences
- essential genes
- computational biology
- multiple sequence alignment
- protein families
- amino acids
- protein structure and function
- secondary structure
- protein function
- protein classification
- sequence analysis
- coarse grained
- biological sequences
- sequence alignment
- multiple alignment
- protein structure
- amino acid composition
- protein structure prediction
- machine learning
- protein structural