Supercoiling in prokaryotic and eukaryotic DNA: changes in response to topological perturbation of plasmids in E. coli and SV40 in vitro, in nuclei and in CV-1 cells.
Franca EspositoRichard R. SindenPublished in: Nucleic Acids Res. (1987)
Keyphrases
- dna sequences
- microscopy images
- cell nuclei
- white blood cells
- binding sites
- dna computing
- topological properties
- microscope images
- microscopic images
- automatic recognition
- human genome
- quantitative analysis
- topological features
- automated detection
- topological spaces
- live cell imaging
- computational methods
- motif discovery
- transcription factor binding sites
- visual stimuli
- basal ganglia