Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of metabolic syndrome.
Melissa J. MorineJolene McMonagleSinead ToomeyClare M. ReynoldsAidan P. MoloneyIsobel Claire GormleyPeadar Ó GaoraHelen M. RochePublished in: BMC Bioinform. (2010)
Keyphrases
- bi directional
- canonical correlation analysis
- gene sets
- gene ontology
- differential expression
- microarray data
- microarray
- least squares
- biologically relevant
- genome wide
- statistical significance
- partial least squares
- gene expression
- metabolic pathways
- data sets
- associative memory
- gene selection
- microarray datasets
- high throughput
- protein protein interactions
- dimensionality reduction methods
- data analysis