Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs.
Linyong MaoW. Jim ZhengPublished in: IMSCCS (1) (2006)
Keyphrases
- motif discovery
- dna binding
- binding sites
- transcription factors
- sequence alignment
- dna sequences
- gene expression
- biological sequences
- regulatory networks
- sequence data
- pattern discovery
- microarray
- component analysis
- protein interaction
- genome wide
- data mining tasks
- transcription factor binding sites
- computational biology
- co occurrence
- statistical significance
- multiobjective optimization
- highly correlated
- data mining
- human genome
- microarray data
- high throughput
- systems biology
- computational models
- data mining algorithms
- data analysis