DNAPred: Accurate Identification of DNA-Binding Sites from Protein Sequence by Ensembled Hyperplane-Distance-Based Support Vector Machines.
Yi-Heng ZhuJun HuXiaoning SongDong-Jun YuPublished in: J. Chem. Inf. Model. (2019)
Keyphrases
- hyperplane
- binding sites
- biological sequences
- protein protein
- protein sequences
- support vector
- genome sequences
- sequence alignment
- sequence data
- dna sequences
- gene expression
- transcription factors
- data points
- motif discovery
- kernel function
- training samples
- feature space
- input space
- sequence analysis
- protein structure
- dna binding
- statistical significance
- amino acids
- support vector machine
- principal components
- computational biology
- support vectors
- convex hull
- transcription factor binding sites
- secondary structure
- protein families
- svm classifier
- genomic data
- feature selection
- learning algorithm
- protein protein interactions
- amino acid sequences
- human genome
- high dimensional
- pairwise
- feature extraction