Optimal design of gene knockout experiments for gene regulatory network inference.
S. M. Minhaz Ud-DeanRudiyanto GunawanPublished in: Bioinform. (2016)
Keyphrases
- optimal design
- gene regulatory networks
- dynamic bayesian networks
- bayesian inference
- undirected graphical models
- gene expression data
- gene networks
- reverse engineering
- network model
- gene interactions
- systems biology
- regulatory networks
- escherichia coli
- gene regulation
- microarray gene expression data
- biological processes
- biological data
- bayesian networks
- interaction networks
- structure learning
- biological networks
- probabilistic model
- approximate inference
- microarray
- metabolic pathways
- prior information
- saccharomyces cerevisiae
- belief networks
- exact inference
- probabilistic inference
- gene expression
- metropolis hastings algorithm
- gene expression profiles
- conditional random fields
- particle filtering
- high dimensional data
- statistical analysis
- data sets
- data analysis