Disentangling evolutionary signals: conservation, specificity determining positions and coevolution. Implication for catalytic residue prediction.
Elin TeppaAngela D. WilkinsMorten NielsenCristina Marino BusljePublished in: BMC Bioinform. (2012)
Keyphrases
- prediction accuracy
- protein structure prediction
- prediction model
- signal processing
- contact map
- prediction error
- evolutionary computation
- neural network
- spectral analysis
- genetic algorithm
- predictive model
- prediction algorithm
- functional dependencies
- multiple sequence alignments
- genetic programming
- evolutionary algorithm
- machine learning