'One DB to rule them all' - the RING: a Regulatory INteraction Graph combining TFs, genes/proteins, SNPs, diseases and drugs.
Gianfranco PolitanoStefano Di CarloAlfredo BensoPublished in: Database J. Biol. Databases Curation (2019)
Keyphrases
- dna binding
- genome wide
- transcription factors
- cis regulatory
- protein interaction
- single nucleotide polymorphisms
- high throughput
- association studies
- gene expression
- genomic data
- saccharomyces cerevisiae
- genome wide association studies
- protein protein interactions
- biological processes
- complex diseases
- binding sites
- arabidopsis thaliana
- dna sequences
- gene regulation
- gene function
- microarray
- biological data
- drug design
- biomedical literature
- disease genes
- regulatory networks
- human genome
- systems biology
- cell cycle
- gene regulatory
- living cells
- protein function
- gene sets
- transcription factor binding sites
- protein protein interaction networks
- protein interaction networks
- functional modules
- transcriptional regulatory
- alternative splicing
- protein complexes
- computational approaches
- linkage disequilibrium
- component analysis
- computational methods
- coding regions
- regulatory elements
- microarray data
- protein interaction data
- gene ontology
- protein function prediction
- signaling pathways