Tree Gibbs Sampler: identifying conserved motifs without aligning orthologous sequences.
Xiaohui CaiHaiyan HuXiaoman Shawn LiPublished in: Bioinform. (2007)
Keyphrases
- transcription factor binding sites
- gibbs sampler
- binding sites
- dna sequences
- bayesian inference
- comparative genomics
- sequence alignment
- sequence similarity
- regulatory elements
- transcription factors
- markov chain
- gibbs sampling
- random fields
- rna sequences
- protein families
- motif discovery
- posterior distribution
- biological sequences
- markov chain monte carlo
- gene regulation
- gene expression
- genomic sequences
- phylogenetic trees
- hyperparameters
- machine learning
- genome wide
- model selection
- sequence data