A novel motif-discovery algorithm to identify co-regulatory motifs in large transcription factor and microRNA co-regulatory networks in human.
Cheng LiangYue LiJiawei LuoZhaolei ZhangPublished in: Bioinform. (2015)
Keyphrases
- transcription factors
- binding sites
- motif discovery
- regulatory networks
- dna sequences
- gene expression
- dna binding
- gene regulation
- sequence data
- genome wide
- protein interaction
- microarray
- transcription factor binding sites
- biological processes
- biological sequences
- statistical significance
- cis regulatory
- component analysis
- systems biology
- co occurrence
- high throughput
- molecular biology
- highly correlated
- computational biology
- automatic extraction
- computational models
- gene expression data
- natural language processing