A DNA shape-based regulatory score improves position-weight matrix-based recognition of transcription factor binding sites.
Jichen YangStephen A. RamseyPublished in: Bioinform. (2015)
Keyphrases
- weight matrix
- transcription factor binding sites
- binding sites
- transcription factors
- dna sequences
- weight matrices
- regulatory elements
- dna binding
- object recognition
- motif discovery
- microarray
- gene expression
- gene regulation
- genome sequences
- component analysis
- genome wide
- level set
- adjacency matrix
- biological sequences
- sequence data
- genomic sequences
- feature extraction
- graph representation
- image segmentation
- human genome
- transition probabilities
- statistical significance
- graph matching
- high dimensionality
- co occurrence
- pattern recognition