Detection of over-represented motifs corresponding to known TFBSs via motif clustering and matching.
Lifang LiuLicheng JiaoPublished in: Comput. Math. Appl. (2010)
Keyphrases
- motif discovery
- transcription factor binding sites
- transcription factors
- dna sequences
- data mining tasks
- binding sites
- motif discovery algorithm
- component analysis
- genome wide
- microarray
- biological sequences
- gene expression
- computational biology
- clustering algorithm
- pattern discovery
- clustering method
- human genome
- high dimensional data
- gene regulation
- motif finding
- dna binding
- k means
- highly correlated
- multiobjective optimization
- data mining
- high dimensionality
- regulatory networks
- biomedical literature
- sequence data
- co occurrence
- factor analysis
- complex networks
- data mining algorithms
- network motifs
- data points
- feature selection