Coevolving residues inform protein dynamics profiles and disease susceptibility of nSNVs.
Brandon M. ButlerI. Can KazanAvishek KumarS. Banu OzkanPublished in: PLoS Comput. Biol. (2018)
Keyphrases
- computational tools
- protein function
- amino acid sequences
- protein chains
- physiological processes
- protein structure
- protein protein
- computational approaches
- amino acids
- dynamical systems
- protein sequences
- user profiles
- psi blast
- cellular processes
- physicochemical properties
- tertiary structure
- protein structure alignment
- protein structure prediction
- amino acid composition
- protein tertiary structure
- contact map
- experimentally determined
- protein protein interaction networks
- behavioral patterns
- protein folding
- sequence alignment
- secondary structure