Prioritization of candidate genes based on disease similarity and protein's proximity in PPI networks.
Gamage Upeksha GanegodaJianxin WangFang-Xiang WuMin LiPublished in: BIBM (2013)
Keyphrases
- candidate genes
- protein protein interactions
- ppi networks
- protein complexes
- protein protein interaction networks
- cellular processes
- disease genes
- protein interaction
- gene clusters
- gene ontology
- protein interaction networks
- gene selection
- functional modules
- similarity measure
- computational methods
- biological knowledge
- high throughput
- computational approaches
- genomic data
- biological networks
- biomedical literature
- biological data
- structural properties
- semantic similarity
- high precision
- biological processes
- network analysis
- microarray data
- microarray
- protein structure
- gene networks
- clustering method
- natural language processing
- gene expression
- complex diseases
- protein sequences
- computational biology
- sequence data
- social networks