Identification of Multitarget Activity Ridges in High-Dimensional Bioactivity Spaces.
Disha Gupta-OstermannJürgen BajorathPublished in: J. Chem. Inf. Model. (2012)
Keyphrases
- data mining
- high dimensional
- low dimensional
- discrete data
- machine learning
- sparse data
- dimensionality reduction
- multi modal
- drug discovery
- automatic identification
- gray level
- similarity search
- metric space
- nearest neighbor
- multiscale
- scale space
- database
- human activities
- microarray data
- input space
- data points
- feature space
- principal component analysis
- high dimensional data
- activity patterns