Identification of hot regions in hub protein-protein interactions by clustering and PPRA optimization.
Xiaoli LinXiaolong ZhangPublished in: BMC Medical Informatics Decis. Mak. (2021)
Keyphrases
- protein protein interactions
- computational methods
- high throughput
- predicting protein protein interactions
- functional modules
- biological processes
- protein interaction
- biological data
- biomedical literature
- systems biology
- network topology
- k means
- gene ontology
- clustering algorithm
- protein protein
- clustering method
- information theoretic
- high precision
- biological networks
- protein function
- protein complexes
- network analysis
- computational approaches
- high dimensional data
- database systems
- wet lab
- protein interaction networks
- high speed
- cluster analysis
- social network analysis
- complex networks
- structural properties