How and when should interactome-derived clusters be used to predict functional modules and protein function?
Jimin SongMona SinghPublished in: Bioinform. (2009)
Keyphrases
- protein function
- functional modules
- protein protein interactions
- protein interaction networks
- protein interaction
- computational methods
- biological networks
- protein complexes
- high throughput
- biological processes
- complex networks
- gene ontology
- network topology
- information flow
- biomedical literature
- amino acids
- clustering algorithm
- genomic data
- protein sequences
- biological data
- gene expression
- gene expression profiles
- protein structure
- structural properties
- microarray
- data sets
- systems biology
- cluster analysis
- computational tools
- knowledge discovery
- data model
- computational approaches
- high precision
- network analysis