Identification of Essential Proteins by Detecting Topological and Functional Clusters in Protein Interaction Network of Saccharomyces Cerevisiae.
Kaustav SenguptaSovan SahaPiyali ChatterjeeMahantapas KunduMita NasipuriSubhadip BasuPublished in: Int. J. Nat. Comput. Res. (2019)
Keyphrases
- essential proteins
- protein interaction networks
- saccharomyces cerevisiae
- protein protein interactions
- protein complexes
- functional modules
- drug design
- protein function
- complex networks
- protein protein interaction networks
- microarray data
- biological networks
- network topology
- biological data
- high throughput
- cell cycle
- biological processes
- regulatory networks
- cluster analysis
- minimum spanning tree
- gene expression data
- gene regulatory networks
- clustering coefficient
- protein interaction
- biomedical literature
- systems biology
- signaling pathways
- network analysis
- computational methods
- genomic data
- interaction networks
- gene regulation
- information flow
- gene expression