Persistent spectral based ensemble learning (PerSpect-EL) for protein-protein binding affinity prediction.
Junjie WeeKelin XiaPublished in: Briefings Bioinform. (2022)
Keyphrases
- ensemble learning
- ensemble methods
- prediction accuracy
- protein protein
- predicting protein
- drug design
- generalization ability
- protein protein interactions
- computational methods
- random forest
- base classifiers
- prediction model
- protein sequences
- unlabeled data
- protein interaction
- interaction networks
- pairwise
- feature selection
- high throughput
- systems biology
- multi class
- training data