Estimating Genome-Wide Copy Number Using Allele-Specific Mixture Models.
Wenyi WangBenilton S. CarvalhoNathaniel D. MillerJonathan PevsnerAravinda ChakravartiRafael A. IrizarryPublished in: J. Comput. Biol. (2008)
Keyphrases
- mixture model
- genome wide
- high throughput
- dna copy number
- em algorithm
- generative model
- copy number
- single nucleotide polymorphisms
- probabilistic model
- expectation maximization
- human genome
- unsupervised learning
- maximum likelihood
- language model
- data sets
- model selection
- systems biology
- biological data
- feature vectors
- decision trees
- image processing
- feature selection
- information retrieval