PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs.
Sylvain PitreFrank K. H. A. DehneAlbert ChanJames CheethamAlex DuongAndrew EmiliMarinella GebbiaJack GreenblattMatthew JessulatNevan J. KroganXuemei LuoAshkan GolshaniPublished in: BMC Bioinform. (2006)
Keyphrases
- protein protein interactions
- protein interaction
- interacting proteins
- amino acid residues
- protein sequences
- multiple sequence alignments
- amino acids
- protein function
- predicting protein
- experimentally determined
- amino acid sequences
- protein protein
- protein interaction data
- secondary structure
- drug design
- high throughput
- computational methods
- predicting protein protein interactions
- protein structure
- high throughput experimental
- protein complexes
- biological processes
- biological sequences
- functional modules
- sequence analysis
- wet lab
- pairwise
- network topology
- gene ontology
- computational biology
- cellular processes
- biomedical literature
- protein interaction networks
- high precision
- computational approaches
- multiple sequence alignment
- genomic data
- ppi networks
- sequence alignment
- protein function prediction
- biological data
- saccharomyces cerevisiae
- essential proteins
- systems biology
- dna binding
- gene expression
- structural properties
- biological systems
- computational tools
- sequence similarity
- interaction networks
- protein protein interaction networks