Known allosteric proteins have central roles in genetic disease.
György AbrusánDavid B. AscherMichael InouyePublished in: PLoS Comput. Biol. (2022)
Keyphrases
- disease genes
- biological knowledge
- complex diseases
- protein protein interaction networks
- linkage disequilibrium
- genome wide association studies
- protein protein interactions
- gene gene interactions
- genome wide
- genetic algorithm
- biological entities
- genetic variation
- gene expression
- computational methods
- human genome
- linkage analysis
- biological systems
- amino acids
- high throughput
- copy number
- disease diagnosis
- molecular level
- protein sequences
- gene function
- sequence similarity
- signaling pathways
- biomedical literature
- subcellular localization
- protein structure
- gene gene
- signal transduction pathways